Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling
Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Tiam1 encodes an exchange factor for the Rho-like guanosine triphosphatase Rac. Both Tiam1 and activated RacV12 promote invasiveness of T lymphoma cells. In epithelial Madin–Darby canine kidney (MDCK) cells, Tiam1 localized to adherens junctions. Ectopic expression of Tiam1 or RacV12 inhibited hepatocyte growth factor–induced scattering by increasi...
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Full title
Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling
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TN_cdi_proquest_miscellaneous_79421310
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79421310
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.278.5342.1464
