High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcino...
High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay
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Basingstoke: Nature Publishing
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English
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Basingstoke: Nature Publishing
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To determine the timing and actual incidence of p53 mutations in oral epithelial lesions, we examined 33 primary squamous cell carcinomas (SCCs), 14 dysplasias and six hyperplasias from Japanese patients by a combination of yeast functional assay and DNA sequencing. The assay detects mutations of p53 mRNA between codons 67 and 347 on the basis of t...
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High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay
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TN_cdi_proquest_miscellaneous_79459392
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79459392
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1201438
