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Cloning of an Interleukin-3 Receptor Gene: A Member of a Distinct Receptor Gene Family

Cloning of an Interleukin-3 Receptor Gene: A Member of a Distinct Receptor Gene Family

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79587854

Cloning of an Interleukin-3 Receptor Gene: A Member of a Distinct Receptor Gene Family

About this item

Full title

Cloning of an Interleukin-3 Receptor Gene: A Member of a Distinct Receptor Gene Family

Publisher

Washington, DC: American Society for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1990-01, Vol.247 (4940), p.324-327

Language

English

Formats

Publication information

Publisher

Washington, DC: American Society for the Advancement of Science

More information

Scope and Contents

Contents

Interleukin-3 (IL-3) binds to its receptor with high and low affinities, induces tyrosine phosphorylation, and promotes the proliferation and differentiation of hematopoietic cells. A binding component of the IL-3 receptor was cloned. Fibroblasts transfected with the complementary DNA bound IL-3 with a low affinity [dissociation constant ($K_d$) of...

Alternative Titles

Full title

Cloning of an Interleukin-3 Receptor Gene: A Member of a Distinct Receptor Gene Family

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_79587854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79587854

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.2404337

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