Doxycycline Reduces Mortality to Lethal Endotoxemia by Reducing Nitric Oxide Synthesis via an Interl...
Doxycycline Reduces Mortality to Lethal Endotoxemia by Reducing Nitric Oxide Synthesis via an Interleukin-10-Independent Mechanism
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Chicago, IL: The University of Chicago Press
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English
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Chicago, IL: The University of Chicago Press
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It was demonstrated that doxycycline protected BALB/c mice injected intraperitoneally with bacterial lipopolysaccharide (LPS) against lethal septic shock. Doxycycline (at 1.5 mg/kg) exerted its protective effect by inhibiting nitrate production by an interleukin-10-independent mechanism. Experiments carried out in vitro also indicated that doxycycl...
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Full title
Doxycycline Reduces Mortality to Lethal Endotoxemia by Reducing Nitric Oxide Synthesis via an Interleukin-10-Independent Mechanism
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TN_cdi_proquest_miscellaneous_79686718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79686718
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1086/517383
