The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C
The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C
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United States
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English
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United States
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Profilin is generally thought to regulate actin polymerization, but the observation that acidic phospholipids dissociate the complex of profilin and actin raised the possibility that profilin might also regulate lipid metabolism. Profilin isolated from platelets binds with high affinity to small clusters of phosphatidylinositol 4,5-bisphosphate (PI...
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The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C
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TN_cdi_proquest_miscellaneous_79703340
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79703340
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ISSN
0036-8075
DOI
10.1126/science.2157283
