A Combination of Oral Sildenafil and Beraprost Ameliorates Pulmonary Hypertension in Rats
A Combination of Oral Sildenafil and Beraprost Ameliorates Pulmonary Hypertension in Rats
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Publisher
New York, NY: Am Thoracic Soc
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Language
English
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Publisher
New York, NY: Am Thoracic Soc
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Contents
Sildenafil, an oral phosphodiesterase type-5 inhibitor, has vasodilatory effects through a cyclic guanosine 3', 5'-monophosphate-dependent mechanism, whereas beraprost, an oral prostacyclin analog, induces vasorelaxation through a cAMP-dependent mechanism. We investigated whether the combination of oral sildenafil and beraprost is superior to each...
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Full title
A Combination of Oral Sildenafil and Beraprost Ameliorates Pulmonary Hypertension in Rats
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TN_cdi_proquest_miscellaneous_80073438
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80073438
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ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.200303-346OC
