High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division
High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Antigen-driven CD8 memory T cell proliferation is more rapid than that of naive T cells, ensuring efficient control of the pathogen after reinfection. We show here that naive and memory cells are in different states of G0/G1 arrest. Naive cells are in a classical state of G0/G1 arrest, with high expression of p27
Kip1
and low CDK6 and CDK2 ki...
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Full title
High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division
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TN_cdi_proquest_miscellaneous_80077447
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80077447
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni1015
