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Steroids Induce Acetylcholine Receptors on Cultured Human Muscle: Implications for Myasthenia Gravis

Steroids Induce Acetylcholine Receptors on Cultured Human Muscle: Implications for Myasthenia Gravis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80109797

Steroids Induce Acetylcholine Receptors on Cultured Human Muscle: Implications for Myasthenia Gravis

About this item

Full title

Steroids Induce Acetylcholine Receptors on Cultured Human Muscle: Implications for Myasthenia Gravis

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1990-10, Vol.87 (20), p.8100-8104

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Antibodies to the acetylcholine receptor (AChR), which are diagnostic of the human autoimmune disease myasthenia gravis, block AChR function and increase the rate of AChR degradation leading to impaired neuromuscular transmission. Steroids are frequently used to alleviate symptoms of muscle fatigue and weakness in patients with myasthenia gravis be...

Alternative Titles

Full title

Steroids Induce Acetylcholine Receptors on Cultured Human Muscle: Implications for Myasthenia Gravis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_80109797

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80109797

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.87.20.8100