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Dynamics of the p53-Mdm2 feedback loop in individual cells

Dynamics of the p53-Mdm2 feedback loop in individual cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80127577

Dynamics of the p53-Mdm2 feedback loop in individual cells

About this item

Full title

Dynamics of the p53-Mdm2 feedback loop in individual cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2004-02, Vol.36 (2), p.147-150

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The tumor suppressor p53, one of the most intensely investigated proteins
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, is usually studied by experiments that are averaged over cell populations, potentially masking the dynamic behavior in individual cells. We present a system for following, in individual living cells, the dynamics of p53 and it...

Alternative Titles

Full title

Dynamics of the p53-Mdm2 feedback loop in individual cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_80127577

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80127577

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng1293

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