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Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the...

Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80141938

Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene

About this item

Full title

Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene

Publisher

Boston, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2004-02, Vol.350 (6), p.570-577

Language

English

Formats

Publication information

Publisher

Boston, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

Insulin-like growth factor I (IGF-I) circulates predominantly as a 150-kD ternary complex that includes the ligand itself, IGF-binding protein 3, and an acid-labile subunit that stabilizes the complex. This report describes a 17-year-old boy with delayed onset and progression of puberty and yet minimal slowing of his linear growth. The boy was foun...

Alternative Titles

Full title

Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_80141938

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80141938

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa013100

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