Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the...
Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene
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Publisher
Boston, MA: Massachusetts Medical Society
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Language
English
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Publisher
Boston, MA: Massachusetts Medical Society
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Contents
Insulin-like growth factor I (IGF-I) circulates predominantly as a 150-kD ternary complex that includes the ligand itself, IGF-binding protein 3, and an acid-labile subunit that stabilizes the complex. This report describes a 17-year-old boy with delayed onset and progression of puberty and yet minimal slowing of his linear growth. The boy was foun...
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Full title
Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene
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Record Identifier
TN_cdi_proquest_miscellaneous_80141938
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80141938
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa013100