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Defective Myoblasts Identified in Duchenne Muscular Dystrophy

Defective Myoblasts Identified in Duchenne Muscular Dystrophy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80588366

Defective Myoblasts Identified in Duchenne Muscular Dystrophy

About this item

Full title

Defective Myoblasts Identified in Duchenne Muscular Dystrophy

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1983-08, Vol.80 (15), p.4856-4860

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A defect in the proliferative capacity of satellite cells, mononucleated precursors of mature muscle fibers, was found in clonal analyses of cells cultured from Duchenne muscular dystrophy (DMD) patients. The total yield of myoblasts per gram of muscle biopsy was decreased to 5% of normal. Of the DMD myoblast clones obtained, a large proportion con...

Alternative Titles

Full title

Defective Myoblasts Identified in Duchenne Muscular Dystrophy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_80588366

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80588366

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.80.15.4856

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