Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent f...
Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
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Publisher
London: Nature Publishing
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Language
English
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Publisher
London: Nature Publishing
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Contents
Haemolysin secreted by pathogenic Escherichia coli binds to mammalian cell membranes, disrupting cellular activities and lysing cells by pore-formation. It is synthesized as nontoxic prohaemolysin (proHlyA), which is activated intracellularly by a mechanism dependent on the cosynthesized HlyC. Haemolysin is one of a family of membrane-targeted toxi...
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Full title
Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
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TN_cdi_proquest_miscellaneous_80658655
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80658655
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/351759a0
