Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation
Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation
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Washington, DC: American Society for the Advancement of Science
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Language
English
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Washington, DC: American Society for the Advancement of Science
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Contents
Mutations that cause pituitary dwarfism in the mouse reside in the gene encoding the transcription factor growth hormone factor 1 (GHF1 or pit1). These dwarf mice (dw and dw$^J$) are deficient in growth hormone (GH) and prolactin (PRL) synthesis and exhibit pituitary hypoplasia, suggesting a stem cell defect. With antisense oligonucleotide technolo...
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Full title
Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation
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TN_cdi_proquest_miscellaneous_80689264
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80689264
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1677216
