Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tubercul...
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Expression of early secreted antigenic target protein 6 (ESAT-6) by
Mycobacterium tuberculosis
is associated with lower innate immune responses to infection. Here we show that ESAT-6 inhibited activation of transcription factor NF-κB and interferon-regulatory factors (IRFs) after Toll-like receptor (TLR) signaling; inhibition of TLR signaling...
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Full title
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
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TN_cdi_proquest_miscellaneous_807270116
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_807270116
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ISSN
1529-2908
E-ISSN
1529-2916,1365-2567
DOI
10.1038/ni1468
