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Oncogene inactivation in a mouse model

Oncogene inactivation in a mouse model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_807272213

Oncogene inactivation in a mouse model

About this item

Full title

Oncogene inactivation in a mouse model

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2000-08, Vol.406 (6795), p.473-474

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tissue invasion by leukaemic cells is stalled by loading them with a designer ribozyme.
Chronic myelogenous leukaemia (CML) is a haematopoietic malignant disease associated with the expression of a chimaeric
BCR–ABL
gene
1
,
2
. We have designed an allosterically controllable ribozyme that specifically cleaves
BCR–ABL
mes...

Alternative Titles

Full title

Oncogene inactivation in a mouse model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_807272213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_807272213

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/35020190

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