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Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link...

Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_807288734

Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link to human retinal degeneration

About this item

Full title

Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link to human retinal degeneration

Publisher

Netherlands: Springer Nature B.V

Journal title

Molecular and cellular biochemistry, 2002-01, Vol.230 (1-2), p.139-147

Language

English

Formats

Publication information

Publisher

Netherlands: Springer Nature B.V

More information

Scope and Contents

Contents

Cyclic GMP is essential for the ability of rods and cones to respond to the light stimuli. Light triggers hydrolysis of cGMP and stops the influx of sodium and calcium through the cGMP-gated ion channels. The consequence of this event is 2-fold: first, the decrease in the inward sodium current plays the major role in an abrupt hyperpolarization of...

Alternative Titles

Full title

Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link to human retinal degeneration

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_807288734

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_807288734

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1023/A:1014248208584

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