Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of...
Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of cytogenetic aberration at 10q24: a study from the Children's Cancer Group (CCG)
About this item
Full title
Author / Creator
Kees, U R , Heerema, N A , Kumar, R , Watt, P M , Baker, D L , La, M K , Uckun, F M and Sather, H N
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Clonal genetic aberrations in tumour cells provide critical information for the development of new diagnostic and therapeutic strategies for patients. In paediatric T-cell acute lymphoblastic leukaemia (T-ALL) chromosomal translocations are present in 30–35% of cases.
HOX11
and the closely related
HOX11L2
genes play a key role in T-ALL....
Alternative Titles
Full title
Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of cytogenetic aberration at 10q24: a study from the Children's Cancer Group (CCG)
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_817602911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_817602911
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/sj.leu.2402892
