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Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups define...

Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups define...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_817602964

Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status

About this item

Full title

Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status

Publisher

London: Nature Publishing

Journal title

Leukemia, 2006-10, Vol.20 (10), p.1774-1782

Language

English

Formats

Publication information

Publisher

London: Nature Publishing

Subjects

Subjects and topics

More information

Scope and Contents

Contents

B-cell chronic lymphocytic leukaemia (B-CLL) is a heterogenous disease with a highly variable clinical course and analysis of zeta-associated protein 70 (ZAP-70) and CD38 expression on B-CLL cells allowed for identification of patients with good (ZAP-70-CD38-) and poor (ZAP-70+CD38+) prognosis. DNA microarray technology was employed to compare eigh...

Alternative Titles

Full title

Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_817602964

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_817602964

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/sj.leu.2404363

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