Pressure Effect on the Membrane Action of a Nerve-Blocking Spin Label
Pressure Effect on the Membrane Action of a Nerve-Blocking Spin Label
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
A reversible nerve-blocking spin label, 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) was used to study the nature of anesthetic-binding sites in nerve membranes as a function of pressure. The nerve-blocking effect of TEMPO is enhanced under pressure. At atmospheric pressure, TEMPO blocks nerve conduction by solubilizing in the apolar region of the...
Alternative Titles
Full title
Pressure Effect on the Membrane Action of a Nerve-Blocking Spin Label
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_82199577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_82199577
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.70.11.3179
