CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels
CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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United States: American Association for the Advancement of Science
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Contents
Voltage- and store-operated calcium (Ca²⁺) channels are the major routes of Ca²⁺ entry in mammalian cells, but little is known about how cells coordinate the activity of these channels to generate coherent calcium signals. We found that STIM1 (stromal interaction molecule 1), the main activator of store-operated Ca²⁺ channels, directly suppresses d...
Alternative Titles
Full title
CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels
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Record Identifier
TN_cdi_proquest_miscellaneous_831203598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_831203598
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1191027
