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Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_839661188

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

About this item

Full title

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2007-06, Vol.9 (6), p.625-635

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The pluripotency of embryonic stem (ES) cells is thought to be maintained by a few key transcription factors, including Oct3/4 and Sox2. The function of Oct3/4 in ES cells has been extensively characterized, but that of Sox2 has yet to be determined. Sox2 can act synergistically with Oct3/4 in vitro to activate Oct–Sox enhancers, which regulate the...

Alternative Titles

Full title

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_839661188

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_839661188

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb1589

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