Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The pluripotency of embryonic stem (ES) cells is thought to be maintained by a few key transcription factors, including Oct3/4 and Sox2. The function of Oct3/4 in ES cells has been extensively characterized, but that of Sox2 has yet to be determined. Sox2 can act synergistically with Oct3/4 in vitro to activate Oct–Sox enhancers, which regulate the...
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Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
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TN_cdi_proquest_miscellaneous_839661188
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_839661188
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1589