Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cerebral malaria claims more than 1 million lives per year. We report that heme oxygenase-1 (HO-1, encoded by
Hmox1
) prevents the development of experimental cerebral malaria (ECM). BALB/c mice infected with
Plasmodium berghei
ANKA upregulated HO-1 expression and activity and did not develop ECM. Deletion of
Hmox1
and inhibition...
Alternative Titles
Full title
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_839674596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_839674596
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1586
