Interferon-γ links ultraviolet radiation to melanomagenesis in mice
Interferon-γ links ultraviolet radiation to melanomagenesis in mice
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Author / Creator
Zaidi, M. Raza , Davis, Sean , Noonan, Frances P. , Graff-Cherry, Cari , Hawley, Teresa S. , Walker, Robert L. , Feigenbaum, Lionel , Fuchs, Elaine , Lyakh, Lyudmila , Young, Howard A. , Hornyak, Thomas J. , Arnheiter, Heinz , Trinchieri, Giorgio , Meltzer, Paul S. , De Fabo, Edward C. and Merlino, Glenn
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
How UV induces melanoma
Exposure to ultraviolet (UV) radiation has been implicated in melanoma formation. Glenn Merlino and colleagues now show, in a mouse model, that UVB irradiation induces the recruitment of macrophages that produce interferon-γ to promote melanoma formation. The study suggests that agents that target interferon-γ may have th...
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Full title
Interferon-γ links ultraviolet radiation to melanomagenesis in mice
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TN_cdi_proquest_miscellaneous_848321491
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_848321491
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09666
