Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Selectively targeting cancer stem cells with novel therapeutics is gaining importance because disease recurrence after treatment-induced remissions is a major cause of morbidity and mortality. This Review discusses the pathways that are active during development, specifically the Wnt, Notch, and Hedgehog pathways, and the clinical development of th...
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Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
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TN_cdi_proquest_miscellaneous_848689003
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_848689003
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2010.196