Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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With the capacity for rapid self-renewal and regeneration, the intestinal epithelium is stereotypical of stem cell-supported tissues. Yet the pattern of stem cell turnover remains in question. Applying analytical methods from population dynamics and statistical physics to an inducible genetic labeling system, we showed that clone size distributions...
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Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
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TN_cdi_proquest_miscellaneous_849471396
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_849471396
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1196236