Molecular Mechanism of NLRP3 Inflammasome Activation
Molecular Mechanism of NLRP3 Inflammasome Activation
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Publisher
Boston: Boston : Springer US
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Language
English
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Publisher
Boston: Boston : Springer US
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Contents
The inflammasome is an intracellular multimolecular complex that controls caspase-1 activity in the innate immune system. NLRP3, a member of the NLR family of cytosolic pattern recognition receptors, along with the adaptor protein ASC, mediates caspase-1 activation via assembly of the inflammasome in response to various pathogen-derived factors as...
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Full title
Molecular Mechanism of NLRP3 Inflammasome Activation
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TN_cdi_proquest_miscellaneous_851461341
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851461341
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ISSN
0271-9142
E-ISSN
1573-2592
DOI
10.1007/s10875-010-9440-3
