The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunor...
The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Dendritic cells (DCs) can promote or inhibit T cell responses. Grogan and colleagues show that the T cell protein TIGIT, by engaging poliovirus receptor on DCs, promotes DC interleukin 10 production, which inhibits T cell activation.
Here we have identified a surface protein, TIGIT, containing an immunoglobulin variable domain, a transmembrane d...
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The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
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TN_cdi_proquest_miscellaneous_851461417
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851461417
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1674
