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Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851467099

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

About this item

Full title

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2001-11, Vol.2 (11), p.1032-1039

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Expression of peripheral antigens in the thymus has been implicated in T cell tolerance and autoimmunity. Here we identified medullary thymic epithelial cells as being a unique cell type that expresses a diverse range of tissue-specific antigens. We found that this promiscuous gene expression was a cell-autonomous property of medullary epithelial c...

Alternative Titles

Full title

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_851467099

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851467099

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni723

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