The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
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Author / Creator
Sapieha, Przemyslaw , Sirinyan, Mirna , Hamel, David , Zaniolo, Karine , Joyal, Jean-Sébastien , Cho, Jang-Hyeon , Honoré, Jean-Claude , Kermorvant-Duchemin, Elsa , Varma, Daya R , Tremblay, Sophie , Leduc, Martin , Rihakova, Lenka , Hardy, Pierre , Klein, William H , Mu, Xiuqian , Mamer, Orval , Lachapelle, Pierre , Di Polo, Adriana , Beauséjour, Christian , Andelfinger, Gregor , Mitchell, Grant , Sennlaub, Florian and Chemtob, Sylvain
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The mechanisms that control blood vessel formation are incompletely understood. Sylvain Chemtob and his colleagues now find that blood vessel formation in mouse and rat retinas is controlled by succinate generated during hypoxic and ischemic conditions. Succinate acting through its receptor, GPR91, on retinal ganglion neurons, triggers secretion of...
Alternative Titles
Full title
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
Authors, Artists and Contributors
Author / Creator
Sirinyan, Mirna
Hamel, David
Zaniolo, Karine
Joyal, Jean-Sébastien
Cho, Jang-Hyeon
Honoré, Jean-Claude
Kermorvant-Duchemin, Elsa
Varma, Daya R
Tremblay, Sophie
Leduc, Martin
Rihakova, Lenka
Hardy, Pierre
Klein, William H
Mu, Xiuqian
Mamer, Orval
Lachapelle, Pierre
Di Polo, Adriana
Beauséjour, Christian
Andelfinger, Gregor
Mitchell, Grant
Sennlaub, Florian
Chemtob, Sylvain
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_853469453
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_853469453
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.1873
