Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Here we investigated the potential role of bone-resorbing osteoclasts in homeostasis and stress-induced mobilization of hematopoietic progenitors. Different stress situations induced activity of osteoclasts (OCLs) along the stem cell–rich endosteum region of bone, secretion of proteolytic enzymes and mobilization of progenitors. Specific stimulatio...
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Full title
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
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TN_cdi_proquest_miscellaneous_853479580
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_853479580
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1417
