How APC/C–Cdc20 changes its substrate specificity in mitosis
How APC/C–Cdc20 changes its substrate specificity in mitosis
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
APC/C-Cdc20 ubiquitylates different substrates at distinct times during the cell cycle. This substrate specificity is now shown to depend on the differential binding of Cdc20 to APC subunits in response to the state of activation of the spindle assembly checkpoint.
Progress through mitosis requires that the right protein be degraded at the right...
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Full title
How APC/C–Cdc20 changes its substrate specificity in mitosis
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TN_cdi_proquest_miscellaneous_855198450
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855198450
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/ncb2165
