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Targeted therapy in GIST: in silico modeling for prediction of resistance

Targeted therapy in GIST: in silico modeling for prediction of resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855199727

Targeted therapy in GIST: in silico modeling for prediction of resistance

About this item

Full title

Targeted therapy in GIST: in silico modeling for prediction of resistance

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Clinical oncology, 2011-03, Vol.8 (3), p.161-170

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

New techniques, such as crystallography and three-dimensional modeling, can be used to assist the development of selective targeted agents for cancer treatment. In this Review, Pierotti and colleagues discuss the molecular features of KIT and PDGFRA receptor tyrosine kinases, which are druggable targets in gastrointestinal stromal tumors. The autho...

Alternative Titles

Full title

Targeted therapy in GIST: in silico modeling for prediction of resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_855199727

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855199727

Other Identifiers

ISSN

1759-4774

E-ISSN

1759-4782

DOI

10.1038/nrclinonc.2011.3

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