Bace1 modulates myelination in the central and peripheral nervous system
Bace1 modulates myelination in the central and peripheral nervous system
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Bace1 is an endopeptidase that cleaves the amyloid precursor protein at the β-secretase site. Apart from this cleavage, the functional importance of Bace1 in other physiological events is unknown. We show here that Bace1 regulates the process of myelination and myelin sheath thickness in the central and peripheral nerves. In
Bace1
-null mice,...
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Bace1 modulates myelination in the central and peripheral nervous system
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TN_cdi_proquest_miscellaneous_856760190
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_856760190
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1797