Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis
Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis
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Basingstoke: Elsevier Inc
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English
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Basingstoke: Elsevier Inc
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As renal lipotoxicity can lead to chronic kidney disease (CKD), we examined the role of peroxisome proliferator-activated receptor (PPAR)-α, a positive regulator of renal lipolysis. Feeding mice a high-fat diet induced glomerular injury, and treating them with fenofibrate, a PPARα agonist, increased the expression of lipolytic enzymes and reduced l...
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Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis
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TN_cdi_proquest_miscellaneous_859744342
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_859744342
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2010.530
