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Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asth...

Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_859746327

Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asthmatic patients

About this item

Full title

Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asthmatic patients

Publisher

England: Future Medicine Ltd

Journal title

Pharmacogenomics, 2011-03, Vol.12 (3), p.351-363

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

Thromboxane A synthase (TBXAS1) converts prostaglandin H to thromboxane A, a potent constrictor of smooth respiratory muscle. Thus, functional alterations of the
gene may contribute to aspirin-intolerant asthma (AIA).
We investigated the relationship between SNPs in the
gene and AIA. Asthmatics (n = 470) were categorized into AIA (20% or g...

Alternative Titles

Full title

Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asthmatic patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_859746327

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_859746327

Other Identifiers

ISSN

1462-2416

E-ISSN

1744-8042

DOI

10.2217/pgs.10.181

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