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Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the...

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864779861

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway

About this item

Full title

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway

Publisher

Boston: Springer US

Journal title

Apoptosis (London), 2011-06, Vol.16 (6), p.636-651

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Apoptosis is modulated by extrinsic and intrinsic signaling pathways through the formation of the death receptor-mediated death-inducing signaling complex (DISC) and the mitochondrial-derived apoptosome, respectively. Ino-C2-PAF, a novel synthetic phospholipid shows impressive antiproliferative and apoptosis-inducing activity. Little is known about...

Alternative Titles

Full title

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_864779861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864779861

Other Identifiers

ISSN

1360-8185

E-ISSN

1573-675X

DOI

10.1007/s10495-011-0592-2

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