PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos
PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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In eukaryotes,
Suv39h
H3K9 trimethyltransferases are required for pericentric heterochromatin formation and function. In early mouse preimplantation embryos, however, paternal pericentric heterochromatin lacks
Suv39h
-mediated H3K9me3 and downstream marks. Here we demonstrate
Ezh2
-independent targeting of maternally provided poly...
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Full title
PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos
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TN_cdi_proquest_miscellaneous_864953012
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864953012
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.99
