The pharmacokinetics of intravenous paracetamol in neonates: size matters most
The pharmacokinetics of intravenous paracetamol in neonates: size matters most
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Publisher
London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
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Language
English
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Publisher
London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
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Contents
Background The aim was to describe intravenous paracetamol pharmacokinetics, determine major covariates and suggest a dosing regimen for (pre)term neonates. Methods A population pharmacokinetic analysis of 943 paracetamol observations from 158 neonates (27–45 weeks' postmenstrual age (PMA)) was undertaken using non-linear mixed effects models. Data...
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Full title
The pharmacokinetics of intravenous paracetamol in neonates: size matters most
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TN_cdi_proquest_miscellaneous_866530653
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_866530653
Other Identifiers
ISSN
0003-9888
E-ISSN
1468-2044
DOI
10.1136/adc.2010.204552