Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress
Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress
About this item
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Author / Creator
Publisher
Basingstoke: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
Basingstoke: Elsevier Inc
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Scope and Contents
Contents
Hexokinase (HK), the rate-limiting enzyme in glycolysis, controls cell survival by promoting metabolism and/or inhibiting apoptosis. Since HK isoforms I and II have mitochondrial targeting sequences, we attempted to separate the protective effects of HK on cell metabolism from those on apoptosis. We exposed renal epithelial cells to metabolic stres...
Alternative Titles
Full title
Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress
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TN_cdi_proquest_miscellaneous_866533648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_866533648
Other Identifiers
ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2010.532
