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Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a...

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_869573006

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study

About this item

Full title

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2011-06, Vol.12 (6), p.559-567

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

SummaryBackgroundIndividuals with Li-Fraumeni syndrome have a high lifetime risk of developing cancer. We assessed the feasibility and potential clinical effect of a comprehensive surveillance protocol in asymptomatic TP53 mutation carriers in families with this syndrome. MethodsWe implemented a clinical surveillance protocol, using frequent bioche...

Alternative Titles

Full title

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_869573006

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_869573006

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(11)70119-X

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