Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analys...
Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Language
English
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Berlin/Heidelberg: Springer-Verlag
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Contents
The ability of cancer cells to break out of tissue compartments and invade locally gives solid tumours a defining deadly characteristic. One of the first steps of invasion is the remodelling of the surrounding tissue or extracellular matrix (ECM) and a major part of this process is the over-expression of proteolytic enzymes, such as the urokinase-t...
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Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation
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TN_cdi_proquest_miscellaneous_871965713
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_871965713
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ISSN
0303-6812
E-ISSN
1432-1416
DOI
10.1007/s00285-010-0369-1