Antitumor activity of NVP‐AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer c...
Antitumor activity of NVP‐AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins
About this item
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Author / Creator
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Scope and Contents
Contents
Heat shock protein 90 (HSP90) is a molecular chaperone required for the stability of key regulators of cell survival and is an emerging target of cancer therapy. NVP‐AUY922, a novel and potent inhibitor of HSP90, was evaluated against gastric cancer cell lines. NVP‐AUY922 significantly inhibited the proliferation of all tested gastric cancer cell l...
Alternative Titles
Full title
Antitumor activity of NVP‐AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins
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Record Identifier
TN_cdi_proquest_miscellaneous_872125622
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_872125622
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2011.01944.x
