A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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An antidiabetic LRH-1 agonist
Excess liver fat, or steatosis, is an important risk factor for obesity-associated diabetes. A natural product, dilauroyl phosphatidylcholine (DLPC), has now been identified as a possible antisteatosis agent, with therapeutic potential in pre-diabetic people. DLPC activates the orphan nuclear receptor LRH-1, loss of...
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Full title
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
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TN_cdi_proquest_miscellaneous_873704073
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_873704073
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10111
