Notch signalling in solid tumours: a little bit of everything but not all the time
Notch signalling in solid tumours: a little bit of everything but not all the time
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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A causative role for Notch signalling is well established in T cell acute lymphoblastic leukaemias (T-ALLs), which have activating mutations in the Notch genes resulting in a constitutively active pathway. By contrast, solid tumours, which have ample opportunity to activate the pathway, exhibit inappropriate activation by multiple mec...
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Full title
Notch signalling in solid tumours: a little bit of everything but not all the time
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TN_cdi_proquest_miscellaneous_874183041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_874183041
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3035
