Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
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Author / Creator
Bantscheff, Marcus , Hopf, Carsten , Savitski, Mikhail M , Dittmann, Antje , Grandi, Paola , Michon, Anne-Marie , Schlegl, Judith , Abraham, Yann , Becher, Isabelle , Bergamini, Giovanna , Boesche, Markus , Delling, Manja , Dümpelfeld, Birgit , Eberhard, Dirk , Huthmacher, Carola , Mathieson, Toby , Poeckel, Daniel , Reader, Valérie , Strunk, Katja , Sweetman, Gavain , Kruse, Ulrich , Neubauer, Gitte , Ramsden, Nigel G and Drewes, Gerard
Publisher
New York: Nature Publishing Group US
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English
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Publisher
New York: Nature Publishing Group US
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Contents
Bantscheff
et al
. use chemoproteomics to measure the affinity of small molecules for megadalton protein complexes in cell extracts. Differences in the selectivity of HDAC inhibitors observed when native HDAC complexes are compared with their purified catalytic subunits suggest the limitations of using isolated recombinant proteins in certain...
Alternative Titles
Full title
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
Authors, Artists and Contributors
Author / Creator
Hopf, Carsten
Savitski, Mikhail M
Dittmann, Antje
Grandi, Paola
Michon, Anne-Marie
Schlegl, Judith
Abraham, Yann
Becher, Isabelle
Bergamini, Giovanna
Boesche, Markus
Delling, Manja
Dümpelfeld, Birgit
Eberhard, Dirk
Huthmacher, Carola
Mathieson, Toby
Poeckel, Daniel
Reader, Valérie
Strunk, Katja
Sweetman, Gavain
Kruse, Ulrich
Neubauer, Gitte
Ramsden, Nigel G
Drewes, Gerard
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_874197634
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_874197634
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1759
