MicroRNAs 103 and 107 regulate insulin sensitivity
MicroRNAs 103 and 107 regulate insulin sensitivity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A new target for diabetes and obesity drugs
A microRNA (miRNA) microarray analysis of the livers of two mouse models of obesity show that the expression of miRNA-103 and miRNA-107 is upregulated in obesity. Silencing these miRNAs improves glucose homeostasis and insulin sensitivity. Turning them on in liver or fat is sufficient to impair glucose...
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Full title
MicroRNAs 103 and 107 regulate insulin sensitivity
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TN_cdi_proquest_miscellaneous_874481078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_874481078
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10112
