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Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAP...

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAP...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876230001

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

About this item

Full title

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Acta neuropathologica, 2011-06, Vol.121 (6), p.763-774

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Activation of the MAPK signaling pathway has been shown to be a unifying molecular feature in pilocytic astrocytoma (PA). Genetically, tandem duplications at chromosome 7q34 resulting in
KIAA1549

BRAF
fusion genes constitute the most common mechanism identified to date. To elucidate alternative mechanisms of aberrant MAPK activation i...

Alternative Titles

Full title

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_876230001

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876230001

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-011-0817-z

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