Onconase mediated NFKβ downregulation in malignant pleural mesothelioma
Onconase mediated NFKβ downregulation in malignant pleural mesothelioma
About this item
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Author / Creator
Goparaju, C M , Blasberg, J D , Volinia, S , Palatini, J , Ivanov, S , Donington, J S , Croce, C , Carbone, M , Yang, H and Pass, H I
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Treatment of malignant pleural mesothelioma (MPM) with Ranpirnase (Onconase) results in disruption of protein translation and cell apoptosis. We hypothesize that Onconase exerts an effect via downregulation of nuclear factor kappa B (NFKβ) by specific microRNAs (miRNAs) and that interference of this pathway could have implications for MPM resistanc...
Alternative Titles
Full title
Onconase mediated NFKβ downregulation in malignant pleural mesothelioma
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_876247200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876247200
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2010.643
