Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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We investigated the role of hypothalamic insulin signaling in the regulation of energy balance and insulin action in rats through selective decreases in insulin receptor expression in discrete hypothalamic nuclei. We generated an antisense oligodeoxynucleotide directed against the insulin receptor precursor protein and administered this directly in...
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Full title
Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
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TN_cdi_proquest_miscellaneous_877594353
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_877594353
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn0602-861
