Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Direct routes to liver-like cells
Two groups report new approaches that could lead to the generation of hepatocyte-like cells for liver engineering and regenerative medicine. Lijian Hui and colleagues use a combination of Gata4, Hnf1a and Foxa3 overexpression and p19Arf inactivation to convert mouse fibroblasts directly into induced hepatic (iHe...
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Full title
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
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TN_cdi_proquest_miscellaneous_878820657
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_878820657
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10263
